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CAS 51-05-8 Local Anesthetic Drugs Procaine Hydrochloride For Reduce Pain

Categories Local Anesthetic Drugs
Brand Name: Pharmlab
Model Number: 51-05-8
Certification: ISO 9001, USP,GMP
Place of Origin: China
MOQ: 10g
Price: negotiation
Supply Ability: Western Union, MoneyGram, T/T, bitcoin
Delivery Time: 3-5 work days
Packaging Details: Disguised package ; Foil bag
Product name: Procaine HCL
Other name: Procaine Hydrochloride
CAS: 51-05-8
Appearance: white crystals powder
purity: 99%
Grade: Pharmaceutical grade
Molecular formula: C13H21ClN2O2
Molecular weight: 272.77
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Pharmlab Co.,Ltd
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    CAS 51-05-8 Local Anesthetic Drugs Procaine Hydrochloride For Reduce Pain


    Local Anesthetic Drugs Procaine Hydrochloride Procaine HCl for Reduce Pain


    Quick detail


    Product name: Procaine HCL


    Other name: Procaine Hydrochloride


    CAS: 51-05-8


    Appearance: white crystals powder


    purity: 99%


    Trademark: Pharmlab


    Original: China


    Grade: Pharmaceutical grade


    Package: Disguised package ; Foil bag


    Delivery date: 3-5 work days


    Certificate: ISO 9001, USP,GMP


    Payment: Western Union, MoneyGram, T/T, bitcoin


    Shipping: EMS,HKEMS,EUB,ETK,FEDEX,DHL,UPS,Aramex,ETC


    Policy: Re-Shipping Policy


    Molecular formula: C13H21ClN2O2

    Molecular weight:272.77


    COA


    Product nameProcaine HCl
    AppearanceWhite crystalline powder
    Assay (C13H20N2O2·HCl)99.0% to 101.0%99.5%
    Melting point153~158ºC156.5~157.0ºC
    Heavy metals≤20ppm<5ppm
    Acidity≤0.02N NaOH 0.5ml0.3ml
    Chromatographic puritySecondary spots≤0.5%,sum≤1.0%Conforms
    Loss on drying≤1.0%0.06%
    Residue on ignition≤0.15%0.03%
    Bacterial endotoxins≤0.6EU/mg<0.6EU/mg

    Product description


    Procaine HCL is actually a combination of two B vitamins, PAPA (p-aminobenzoic acid) and DE (diethylaminoethanol), buffered and stabilized with benzoic acid and potassium metabisulfite and is more effective in vivo The Pracaine Hydrochloride is PABA and DEAE, a German chemist, first produced by Dr. Albert Einhorn in 1905, and is looking for a simple, addictive anesthetic.


    For many years procaine was used as a simple anesthetic, but soon the researchers began to notice the other therapeutic abilities of the substance. The interest in the experiment was so high. From 1930 to 1951, 165 articles were published on the treatment of various conditions (including arthritis, neuralgia, itching, peptic ulcer, asthma and high blood pressure)


    In the late 1940s, three French doctors - Drs. Gary, Bouden and the State - found that procaine hydrochloride helps to relieve the pain of asthma attacks. Dr. Rene Leriche found that procaine injections help treat certain forms of arthritis, arteritis and blood clots in limbs.


    Product uses


    Procaine HCl is a local anesthetic drug for the amino ester groups. It is mainly used to reduce intramuscular injection of penicillin pain, and also for dental use. As the merchandise name Novocain is everywhere, in some areas procaine is generally known as Novakaine. Its main role is sodium channel blockers. Because of its sympathetic, anti-inflammatory, perfusion enhancement and emotional enhancement, it is used in some countries for treatment.


    The application of procaine leads to inhibition of neuronal activity. Depression causes the nervous system to become allergic, causing anxiety and vibration, resulting in mild to severe convulsions. Studies of animals have shown that the use of procaine causes an increase in dopamine and serotonin levels in the brain. Other problems may vary due to individual tolerance to procaine dose. Central nervous system excitation can cause tension and dizziness, if excessive coordination may lead to respiratory failure. Procaine may also cause myocardial weakness leading to cardiac arrest.


    Procaine can also cause allergic reactions, leading to individual problems of breathing, rash and swelling. The allergic reaction to procaine is usually not against procaine itself, but its metabolite PABA. About one of about 3,000 people has an atypical form of pseudobase esterase, which does not require hydrolysis of ester anesthetics such as procaine, resulting in increased levels of narcotics in the blood and increased toxicity.


    Product discovery and usage


    procaine hydrochloride was first synthesized by German chemist Albert Einhorn in 1905. He is looking for a compound that can be used as an anesthetic, non-toxic, no side effects, no addiction. Dr. Eindhoven is looking for a compound that can replace cocaine as an anesthetic. Cocaine was used as an anesthetic. However, because cocaine is toxic, addictive, destructive to the central nervous system, its use is illegal. Dr. Einhorn was able to produce a compound that showed the properties he was looking for. This new compound he named as procaine.


    "Pro" means replacement, "cocaine" comes from the word cocaine. Because the names are similar, because they are all anesthetized, there is a lot of confusion about the nature of procaine. Sporaine acts as an anesthetic when injected into the muscle, but when taken as a compound in combination, procaine acts as a vitamin. The procaine HCl solution used as an anesthetic was named Norcaine.


    Chemical procaine is the PABA ester of amino alcohol DEAE. PABA (p-aminobenzoic acid) is a "B" vitamin. DEAE, (n, n diethylaminoethanol) is a biologically active precursor of & quot; B & quot; vitamin choline. (Figure 1) procaine is usually used in the form of hydrochloride (procaine HCl) because it is highly water soluble. Oral administration of procaine hydrochloride is mainly absorbed through the small intestine villi into the body. Experiments show that most of the procaine HCl enters the blood completely through the molecular formula. In the blood, procaine HCl is rapidly hydrolyzed into the PABA and DEAE by the enzyme, which is the two components of the procaine molecule. These metabolites are removed by the liver, chemically changed, and excreted in the urine.


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